IRAN ranks first in the region in conducting researches for IVF, treating and recovering infertility and infertility treatment studies. Royan Institute, a world renowned leader in the stem cell world and embryology research, is a massive research and treatment center with many astonishing achievements and developments, providing best paper selection awards and best research achievement awards in many countries throughout the years. IVF in Iran, has managed the first IVF birth (1993) and first frozen embryo birth in Tehran (1996).
IVF In Iran
The main Benefit of Fertility Treatments is achieving the goal of having a baby, and becoming parents. Thankfully, due to the development of new techniques and methods many couples become pregnant every year. Currently, we have witnessed a variety of Fertility Treatments and procedures available. Usually, the noninvasive procedures are used at first. In Vitro Fertilization (IVF) is an assisted reproductive technology (ART) commonly referred to as IVF. it is the process of fertilization by extracting eggs, retrieving a sperm sample, and then manually combining an egg and sperm in a laboratory dish. The embryo(s) is then transferred to the uterus.
High end hospitals with very high success rate, equipped with modern and state-of-the-art technologies in Tehran, Yazd and many more cities offer help and assistance to those in need of fertility care. These centers supply advanced equipment of in vitro fertilizations and offer excellent assistance in reproductive technology.
Services and treatments provided by these centers include Infertility clinics, Cell therapy centers, Stem cell biology and technology, Reproductive biomedicine, Endocrinology & Female fertility, Embryology, Reproductive Genetics, Epidemiology & Reproductive health, Reproductive Imaging and many more.
The best Fertility Treatment Options are:
Artificial Insemination (Donor)
Artificial Insemination with donor sperm (AID) consists of placing sperm obtained from a sperm donor inside the uterus. It offers more chance of pregnancy. In fact Donor is a simple procedure that uses a syringe to place semen into a woman’s vagina to assist her in getting pregnant.
Assisted hatching is a procedure which involves making a gap in the shell (zona) of the embryo before the embryo transfer, to enhance its ability to hatch after forming a blastocyst. Laser-assisted hatching uses focused infrared beams to accurately remove the zona pellucida, to help hatching of the fertilized egg. This technique is faster that other assisted hatching methods, such as acid hatching.
Clomid which is also called serophene is an oral medication, commonly used to treat infertility. Clomid is used to induce ovulation in women that don’t have the ability to develop an egg and ovulate naturally. The aim of this medication is to induce and regulate ovulation. This medical treatment is often used with a combination of other fertility treatments, such as artificial insemination.
Egg and Ovarian Cortex Freezing
Egg and ovarian cortex freezing is procedure involving freezing and storage of the ovarian tissue. Cancer treatments such as chemotherapy or surgical procedures that require removal of the ovaries or uterus, affect women’s reproductive system. Ovarian cortex freezing can be performed before cancer treatments so that these women may become pregnant in the future. After the cancer treatments, the ovarian tissue can be placed inside the body again.
There are many women that don’t have the ability to become pregnant by their own eggs due to various reasons such as chromosomal abnormaly, premauture ovraian failure, previous disease, early menopause or poor quality of the egg. Egg donation is process which enables these women become parents using donated eggs from fertile women during the in vitro fertilizitaion (IVF) process.
Egg donation with Sperm Donation
In vitro fertilization using egg donation with sperm donation is a laboratory procedure which involves placing harvested donor sperm with donor eggs; So that the fertilized egg can become a pre-embryo. The pre-embryo is then transferred to the uterus to keep developing. This method may be recommended for women with uterus problems due to their age or other causes, or men with azoospermia or other sperm abnormality.
Egg freezing involves the extraction, freezing and storage of a woman’s eggs so that they can become pregnant in the future. Egg freezing can be done either by a slow-freeze technique or a flash-freeze method called vitrification. There are many reasons that make one consider egg freezing, including cancer treatments such as chemotherapy or pelvic radiation that may affect the reproductive system, surgical procedures that can damage the ovaries or personal reasons for fertility preservation while delaying childbearing.
Embryo donation is usually done when a couple have completed their family and have excess embryos. Embryo donation can be recommended for women who have gone through the menopause or for couples having the rick of passing on a genetic disease or are unlikely to become parents using their own eggs or sperm for fertility treatment.
Ebryo freezing invloves the freezing and storage of an embyro so it can be used in future ICSI or IVF cycles. There are two different methods for embryo freezing including slow freezing and vitrification. Embryo freezing may be recommended for various reasons like conditions or treatments that affect the reproductive system and fertility or risk of injury or death. In such cases embryo freezing is an effective method to preserve fertility.
Frozen Embryo Transfer Cycle
Frozen embryo transfer (FET) cycle is a procedure which involves thawing the frozen embryo from previous in vitro fertilization (IVF) or donor egg cycle, and then transferring back into the uterus. The appropriate point in the woman’s menstrual cycle to transfer the embryo is determined by techniques such as ultrasound scans blood testing. This method has a high rate of success and doesn’t need a complete IVF cycle.
Intracytoplasmic morphologically selected sperm injection (IMSI) uses a more powerful microscope for sperm selection compared to ICSI. This technique enables specialists to observe the sperm in more detail (such as the nucleus containing the sperm’s genetic material); so sperms with better quality can be selected to increase the pregnancy rates in comparison to the conventional ICSI method.
In Vitro Fertilization (IVF)
IVF is an fertilization process which involves extracting eggs and retreiving sperm samples, anf then joining them in a laboratory dish. After that, the embryo can be transferred to the uterus. The term “in vitro” means outside the body. IVF is an effective type of assisted reproductive technonlogy. IVF may be recommened for various reasons, such as male factor infertility, recurrent pregnancy loss or genetic abnormalities.
In Vitro Maturation (IVM)
IVM is an assisted reproductive technology similar to IVF, which involves extracting eggs from the ovaries before the woman is matured. The eggs are matured in the laboratory prior to fertilization. While in the conventional IVF method, eggs are collected when they are mature. In the IVM procedure, the women doesn’t need to use as many medications and injections as in the IVF method.
Intracytoplasmic sperm injection (ICSI)
Intracytoplasmic sperm injection (ICSI) is an assisted reproductive technology which involves injecting a single sperm directly into a mature egg. Once the egg is fertilized, it can be placed in the woman’s uterus. This procedure is mainly used to treat conditions of male infertility, such as low sperm count, vasectomy or low sperm motility. ICSI may also be recommended if there were problems during previous IVF fertilization processes.
Intrauterine insemination (IUI)
Intrauterine insemination (IUI) is a specific type of artificial insemination used to treat infertility. This procedure involves placing sperm inside the uterus to increase the number of sperm reaching the fallopian tube. The goal of this method is to increase the fertilization chance. Low sperm count or decreased sperm mobility are the most common indications for IUI, however this procedure may be used to treat other conditions such as cervical condition, Ejaculation dysfunction or Unexplained infertility.
IVF with Gender Selection
IVF is an fertilization process which involves fertilizing egg with sperm during a laboratory procedure. After that, the embryo is transferred into the uterus to continue developing. There are two different PGD or PGS screening steps that can be taken in addition to the conventional IVF process. During these examining procedures, the gender of each embryos can be revealed, so when there are both male and female embryos, it can be chosen to use which one to determine the sex of the child.
Sperm donation can be used to fertilize eggs either outside the woman’s body in the laboratory (during IVF process), or inside the uterus (during IUI process). Sperm donation for treating infertility may be recommended if your partner produces little sperm, has vasectomy, is at high risk of passing on a genetic disease, etc. also of you are a single woman, donated sperm can be used for fertility treatment.
Laparoscopic Hysteroscopy and Sonohysterography
The laparoscope is a tiny camera attached to a thin tube that transmits pictures onto monitors. Hysteroscopy procedures can be either diagnostic to diagnose uterus problems or operative to repair and treat some of the uterus conditions such as polyps and fibroids, malformations or adhesions. The sonohysteroscopy method which is also called fluid contrast ultrasound, is similar to hysteroscopy. This procedure uses ultrasound technology to visualize internal structures using ultrasound waves. Sonohysteroscopy is an effective technique for evaluating the uterus before fertility treatments, such as IVF and embryo transfer.
Microdissection TESE (Testicular Sperm Extraction)
Microdissection or microscopic testicular sperm extraction (TESE) involves and surgical procedure to retrieve sperm for using in fertility treatments. This method is used to improve the outcome of sperm retrieval, especially in men with previous unsuccessful sperm retrieval attempts using conventional TESE procedures. Microdissection TESE is usually recommended for men with non-obstructive azoospermia (abnormal sperm production), which is a common cause of infertility in men.
Natural Cycle and ICSI
The natural cycle ICSI involves retrieval of the egg from the woman without any stimulation. During this procedure, only one egg is retrieved per cycle, which has to be done before the natural ovulation of the woman. This method may be recommended for women who had poor quality embryos by using stimulated cycles, or can’t take fertility or stimulation medications
Ovulation Induction (OI)
Ovulation induction involves medical procedures for treating infertility due to conditions such as ovulation disorders or male factor. Medication is used to stimulate mature follicles development in the ovaries of women who are not able to develop mature follicles regularly. The most common medications used for ovulation induction include clomiphene cirate (clomid), metformin, gonadotropins and parlodel.
PESA (Percutaneous Epididymal Sperm Aspiration)
PESA is a procedure which involves the retrieval of sperm from the epididymis for IVF or ICSI processes, by inserting a tiny needle through the scrotum skin. This method may be recommended for men with obstructive azoospermia (zero sperm count) or a blockage in their reproductive tract due to conditions such as vasectomy, infection or congenital abnormality.
Pre-implantation Genetic Screening (PGS)
Pre-implantation Genetic Screening (PGS) involves the removal of one or more cells from an IVF or ICSI embryo to test for Chromosomal abnormalities, which are the main cause of implant embryo failures and miscarriages. This procedure may be recommended for couples being treated by IVF or ICSI due to fertility issues. PGS provides the ability to avoid having a child at a high risk of having genetic disease, before implantation.
Preimplantation Genetic Diagnosis (PGD)
Preimplantation genetic diagnosis (PGD) is procedure used to detect genetic diseases within embryos. This technique provides the ability to avoid passing on certain genetic disorders to the child, before implantation. PGD is especially used when one or both parents has a certain genetic disorder, to check if the embryo is also affected; while PGS is usually performed when it is assumed that parents don’t have any genetic defects and the embryo is tested for aneuploidy.
Although assisted reproductive technology is commonly used for fertility treatment, there are various male and female structural problems causing infertility which need to be treated by surgical procedures. Reproductive surgery can be used to correct problems in women such as tubal obstruction, uterine fibroids and endometriosis using procedures such as laparotomy microsurgery and laparoscopy. It can also treat certain anatomical defects in men using procedures such as varicocelectomy and vasoepididymostomy.
Sperm Freezing (Semen Freezing)
Sperm freezing which is also called sperm cryopreservation, is a procedure involving freezing and storage of sperm so it can be used either for fertility treatments such as artificial insemination, or be donated in future. Sperm freezing may be recommended for various reasons such as conditions or treatments that may affect fertility, low sperm count or vasectomy.
Surrogacy is a procedure which uses one woman’s uterus for implanting an embryo to give birth to a baby for another couple or person. The woman who carries the embryo is called the surrogate. This procedure require IVF to implant the fertilized egg in the surrogate’s uterus. Surrogacy may be a suitable solution if there are conditions that make it dangerous or impossible for you to become pregnant and to give birth, Medical conditions such as malformation or absence of the womb, previous IVF implantation failures or recurrent pregnancy loss.
TESA (Testicular Sperm Aspiration)
TESA is a procedure which involves the retrieval of sperm for IVF or ICSI processes, by inserting a tiny needle through the scrotum skin. This method may be recommended for men with obstructive azoospermia (zero sperm count) or a blockage in their reproductive tract due to conditions such as vasectomy, infection or congenital abnormality. This procedure and its indications are similar to PESA; the difference is that in PESA the sperm is retrieved directly from the epididymis.